Parity-dependent association between TNF-α and LTF gene polymorphisms and clinical mastitis in dairy cattle

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Parity-dependent association between TNF-α and LTF gene polymorphisms and clinical mastitis in dairy cattle

BACKGROUND One major problem in dairy cattle husbandry is the prevalence of udder infections. In today's breeding programmes, top priority is being given to making animal evaluation more cost-effective and reliable and less time-consuming. We proposed tumor necrosis factor α (TNF-α), lactoferrin (LTF) and macrophage-expressed lysozyme (mLYZ) genes as potential DNA markers in the improvement of ...

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Association between interleukin 8 receptor α gene (CXCR1) and mastitis in dairy cattle

The innate immune response plays an important role in the course of bacterial infections. Innate immunity effectiveness relies on the expression of many genes, connected, among others, to the activity of neutrophils. Interleukin 8 (IL-8) receptor α, coded by the CXCR1 gene, is present on the neutrophil surface and binds pro-inflammatory IL-8 with high affinity. This is why the bovine CXCR1 gene...

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بررسی ارتباط چندشکلی ژن عامل نکروزکننده بافتی با نمره سلول های بدنی شیر در گاوهای شیری

Mastitis is one of the most prevalent and costly diseases affecting dairy cattle production. In the present study, effects of tumor necrosis factor (alpha isomer) gene (TNF-α) polymorphisms on milk somatic cell count (SCS) and subclinical mastitis was investigated in 121 Holstein dairy cattle. The polymorphisms of a 303 bp fragment of TNF-α gene were investigated by PBR and PCR-SSCP techniques....

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The Association between TNF-alpha Gene Polymorphisms and Endometriosis in An Iranian Population

Objective Objective: TNF-α is an important cytokine in acute inflammatory response to infective factors. It seems that this response increases in patients with endometriosis due to presence of cytokines such as TNF-α which has been investigated in patients with endometriosis in different populations. This study aimed at examining four polymorphisms; TNF-α -238G/A, -308G/A, -857C/T and -863C/A a...

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Association between the Melanocortin-4 Receptor (MC4R) Gene Polymorphisms and Growth Trait in Sumba Ongole Cattle

Melanocortin-4 receptor (MC4R) gene has been known as a candidate gene for growth traits in livestock. This research was aimed to identify the polymorphism of MC4R gene and its association with growth traits in Sumba Ongole (SO) cattle. The growth traits data consist of body weight and body size. Eighty four blood samples were collected and used for DNA isolation. The...

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ژورنال

عنوان ژورنال: BMC Veterinary Research

سال: 2013

ISSN: 1746-6148

DOI: 10.1186/1746-6148-9-114